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Quick Answer
This serum uses retinaldehyde (retinal) instead of standard retinol — a form that converts to retinoic acid faster in skin, meaning quicker results at a comparable irritation level. Paired with niacinamide and cica for calming, it’s a genuinely interesting option for people who’ve plateaued on regular retinol.

What Is MEDITHERAPY Retinal Skin Booster Serum?
Vitamin A derivatives exist on a spectrum: retinol needs to convert through retinaldehyde before becoming active retinoic acid in skin, while this product uses retinaldehyde directly — skipping one conversion step. That generally means faster results than standard retinol at a similar strength, without jumping all the way to prescription tretinoin.
MEDITHERAPY rounds out the formula with niacinamide for tone and cica (centella asiatica) for calming, aimed at offsetting some of retinaldehyde’s irritation potential.
Why We Recommend It
Retinaldehyde is genuinely underused in mainstream Western skincare despite research suggesting it can outperform standard retinol at comparable concentrations, largely because it’s harder to stabilize in a formula. Getting a well-formulated retinaldehyde serum with calming ingredients built in is a legitimately interesting middle step between over-the-counter retinol and prescription-strength options.
The larger 5.07 fl oz size (styled as a “skin booster” for both face and body) also reflects real confidence in the formula’s tolerability at scale.
Pros
- Retinaldehyde converts to active retinoic acid faster than standard retinol
- Niacinamide and cica help offset irritation while boosting tone and calming
- A genuine step up for people who’ve plateaued on regular retinol
- Large size relative to most retinol-family serums
- Multi-use positioning (face and body) reflects a well-tolerated formula
Cons
- Retinaldehyde can still cause more noticeable irritation than encapsulated retinol for first-time users
- Less widely known/reviewed than mainstream Western retinol brands, so fewer long-term user reports
Who Should Buy MEDITHERAPY Retinal Skin Booster Serum?
A smart pick for anyone who’s used standard retinol consistently for 6+ months and wants to progress toward faster, more noticeable results without moving to a prescription retinoid.
If you’re new to vitamin A derivatives entirely, start with a gentler encapsulated retinol first and work up to retinaldehyde once your skin has built tolerance.
How to Use It
- Start at 1-2 nights per week, even with prior retinol experience.
- Apply to clean, dry skin and follow with moisturizer.
- Daily SPF is essential the following morning.
Our Verdict
A genuinely smart “next step” for retinol veterans — retinaldehyde is an underrated upgrade, and this formula’s calming ingredients make the transition more manageable than jumping straight to prescription-strength options.
Frequently Asked Questions
What is retinaldehyde and how is it different from retinol?
Retinaldehyde (retinal) is one conversion step closer to active retinoic acid than retinol, meaning it typically works faster at a comparable strength, though it can also be slightly more irritating for first-time users.
Is this suitable for retinol beginners?
Not ideally — it’s better suited to those who already have retinol experience and want to progress to a more potent vitamin A derivative.
Can I use this on my body as well as my face?
Yes, it’s formulated and marketed as a multi-use skin booster for both face and body.
Related Guides
See the full Best Anti-Aging & Retinol Products guide for how this compares to the other top picks, or browse all our skincare recommendations.